Reggio, Patricia H. : rechercher sur Z-Library

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1

Structure–activity relationships for 1-alkyl-3-(1-naphthoyl)indoles at the cannabinoid CB1 and CB2 receptors: steric and electronic effects of naphthoyl substituents. New highly selective CB2 receptor agonists

John W. Huffman, Gulay Zengin, Ming-Jung Wu, Jianzhong Lu, George Hynd, Kristen Bushell, Alicia L.S. Thompson, Simon Bushell, Cindy Tartal, Dow P. Hurst, Patricia H. Reggio, Dana E. Selley, Michael P.

Journal:

Bioorganic & Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 546 KB

english, 2005

2

Stereoselective synthesis of the epimeric Δ7-tetrahydrocannabinols

John W. Huffman, W. Kenneth Banner, Grace K. Zoorob, H. Howard Joyner, Patricia H. Reggio, Billy R. Martin, David R. Compton

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 934 KB

english, 1995

3

An Update on Non-CB 1 , Non-CB 2 Cannabinoid Related G-Protein-Coupled Receptors

Morales, Paula, Reggio, Patricia H.

Journal:

Cannabis and Cannabinoid Research

Année:

2017

Langue:

english

Fichier:

PDF, 709 KB

english, 2017

4

3-Indolyl-1-naphthylmethanes: new cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor

John W Huffman, Ross Mabon, Ming-Jung Wu, Jianzhong Lu, Richard Hart, Dow P Hurst, Patricia H Reggio, Jenny L Wiley, Billy R Martin

Journal:

Bioorganic & Medicinal Chemistry

Année:

2003

Langue:

english

Fichier:

PDF, 333 KB

english, 2003

5

Conformational Memories and the Endocannabinoid Binding Site at the Cannabinoid CB1 Receptor

Barnett-Norris, Judy, Hurst, Dow P., Lynch, Diane L., Guarnieri, Frank, Makriyannis, Alex, Reggio, Patricia H.

Journal:

Journal of Medicinal Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 506 KB

english, 2002

6

The therapeutic potential of orphan GPCRs, GPR35 and GPR55

Shore, Derek M., Reggio, Patricia H.

Journal:

Frontiers in Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 1.26 MB

english, 2015

7

An Overview on Medicinal Chemistry of Synthetic and Natural Derivatives of Cannabidiol

Morales, Paula, Reggio, Patricia H., Jagerovic, Nadine

Journal:

Frontiers in Pharmacology

Année:

2017

Langue:

english

Fichier:

PDF, 1.91 MB

english, 2017

8

The Nucleotide-Free State of the Cannabinoid CB2/Gi Complex

Lynch, Diane L., Hurst, Dow P., Reggio, Patricia H.

Journal:

Année:

2020

Langue:

english

Fichier:

PDF, 453 KB

english, 2020

9

ChemInform Abstract: Ligand—Ligand and Ligand—Receptor Approaches to Modeling the Cannabinoid CB1 and CB2 Receptors: Achievements and Challenges

Patricia H. Reggio

Journal:

Année:

1999

Fichier:

PDF, 27 KB

1999

10

ChemInform Abstract: Mild Generation of o-Quinone Methides. Synthesis of (-)-Hexahydrocannabinol and Dihydrocannabidiol.

Tiansheng Wang, Jason P. Burgess, Patricia H. Reggio, Herbert H. Seltzman

Journal:

Année:

2000

Fichier:

PDF, 28 KB

2000

11

Toward the design of cannabinoid CB1 receptor inverse agonists and neutral antagonists

Patricia H. Reggio

Journal:

Drug Development Research

Année:

2009

Langue:

english

Fichier:

PDF, 450 KB

english, 2009

12

Conformational memories with variable bond angles

Robert M. Whitnell, Dow P. Hurst, Patricia H. Reggio, Frank Guarnieri

Journal:

Journal of Computational Chemistry

Année:

2008

Langue:

english

Fichier:

PDF, 1.24 MB

english, 2008

13

Parameterization of Org27569: An allosteric modulator of the cannabinoid CB1 G protein-coupled receptor

Hadley A. Iliff, Diane L. Lynch, Evangelia Kotsikorou, Patricia H. Reggio

Journal:

Journal of Computational Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 959 KB

english, 2011

14

Ligand-Binding Architecture of Human CB2 Cannabinoid Receptor: Evidence for Receptor Subtype-Specific Binding Motif and Modeling GPCR Activation

Ying Pei, Richard W. Mercier, Jenine K. Anday, Ganesh A. Thakur, Alexander M. Zvonok, Dow Hurst, Patricia H. Reggio, David R. Janero, Alexandros Makriyannis

Journal:

Chemistry & Biology

Année:

2008

Langue:

english

Fichier:

PDF, 614 KB

english, 2008

15

Analogs of JHU75528, a PET ligand for imaging of cerebral cannabinoid receptors (CB1): Development of ligands with optimized lipophilicity and binding affinity

Hong Fan, Evangelia Kotsikorou, Alexander F. Hoffman, Hayden T. Ravert, Daniel Holt, Dow P. Hurst, Carl R. Lupica, Patricia H. Reggio, Robert F. Dannals, Andrew G. Horti

Journal:

European Journal of Medicinal Chemistry

Année:

2009

Langue:

english

Fichier:

PDF, 887 KB

english, 2009

16

Agonist alkyl tail interaction with cannabinoid CB1 receptor V6.43/I6.46 groove induces a helix 6 active conformation

Judy Barnett-Norris, Dow P. Hurst, Kurt Buehner, Juan A. Ballesteros, Frank Guarnieri, Patricia H. Reggio

Journal:

International Journal of Quantum Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 680 KB

english, 2002

17

Molecular determinants for binding of methylenedioxytryptamines at 5-HT/LSD receptors

Patricia H. Reggio, Harel Weinstein, Roman Osman, Sid Topiol

Journal:

International Journal of Quantum Chemistry

Année:

1981

Langue:

english

Fichier:

PDF, 611 KB

english, 1981

18

A molecular reactivity template for cannabinoid analgesic activity

Patricia H. Reggio, Vladimir Frecer, Aleksander P. Mazurek

Journal:

International Journal of Quantum Chemistry

Année:

1990

Langue:

english

Fichier:

PDF, 703 KB

english, 1990

19

Computational studies of the 3-Dimensional structure of cyclopenta polycyclic aromatic hydrocarbons containing a gulf region

Ruben E. Venegas, Patricia H. Reggio, James R. Rabinowitz

Journal:

International Journal of Quantum Chemistry

Année:

1992

Langue:

english

Fichier:

PDF, 820 KB

english, 1992

20

A search for properties which produce discrimination between cannabinoid psychoactivity and analgesic activity

Patricia H. Reggio

Journal:

International Journal of Quantum Chemistry

Année:

1992

Langue:

english

Fichier:

PDF, 828 KB

english, 1992

21

Computational methods in drug design: Modeling G protein-coupled receptor monomers, dimers, and oligomers

Patricia H. Reggio

Journal:

The AAPS Journal

Année:

2006

Langue:

english

Fichier:

PDF, 512 KB

english, 2006

22

Cannabinoid CB1 receptor recognition of endocannabinoids via the lipid bilayer: molecular dynamics simulations of CB1 transmembrane helix 6 and anandamide in a phospholipid bilayer

Diane L. Lynch, Patricia H. Reggio

Journal:

Journal of Computer-Aided Molecular Design

Année:

2006

Langue:

english

Fichier:

PDF, 514 KB

english, 2006

23

Synthesis and pharmacology of 1-methoxy analogs of CP-47,497

John W. Huffman, Seon A. Hepburn, Patricia H. Reggio, Dow P. Hurst, Jenny L. Wiley, Billy R. Martin

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 592 KB

english, 2010

24

Lipid bilayer molecular dynamics study of lipid-derived agonists of the putative cannabinoid receptor, GPR55

Evangelia Kotsikorou, Diane L. Lynch, Mary E. Abood, Patricia H. Reggio

Journal:

Chemistry and Physics of Lipids

Année:

2011

Langue:

english

Fichier:

PDF, 2.79 MB

english, 2011

25

Conformational requirements for endocannabinoid interaction with the cannabinoid receptors, the anandamide transporter and fatty acid amidohydrolase

Patricia H. Reggio, Hassimi Traore

Journal:

Chemistry and Physics of Lipids

Année:

2000

Langue:

english

Fichier:

PDF, 506 KB

english, 2000

26

Endocannabinoid tone versus constitutive activity of cannabinoid receptors

Allyn C. Howlett, Patricia H. Reggio, Steven R. Childers, Robert E. Hampson, Nadine M. Ulloa, Dale G. Deutsch

Journal:

British Journal of Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 1.23 MB

english, 2011

27

The Cannabinoid Receptors Volume 1101 || Cannabimimetic Indoles, Pyrroles, and Indenes: Structure–Activity Relationships and Receptor Interactions

Reggio, Patricia H.

Année:

2009

Langue:

english

Fichier:

PDF, 779 KB

english, 2009

28

The Cannabinoid Receptors Volume 727 || Cannabinoid Receptor Signal Transduction Pathways

Reggio, Patricia H.

Année:

2009

Langue:

english

Fichier:

PDF, 440 KB

english, 2009

29

The Cannabinoid Receptors Volume 5b || Cannabinoid Agonist and Inverse Agonist Regulation of G Protein Coupling

Reggio, Patricia H.

Année:

2009

Langue:

english

Fichier:

PDF, 671 KB

english, 2009

30

The Cannabinoid Receptors Volume 817 || Structure–Activity Relationships and Conformational Freedom of CB1 Receptor Antagonists and Inverse Agonists

Reggio, Patricia H.

Année:

2009

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2009

31

The Cannabinoid Receptors Volume 194 || Molecular Biology of Cannabinoid Receptors: Mutational Analyses of the CB Receptors

Reggio, Patricia H.

Année:

2009

Langue:

english

Fichier:

PDF, 691 KB

english, 2009

32

The Cannabinoid Receptors Volume 5b || Models of Cannabinoid Inverse Agonism, Neutral Antagonism, and Agonism: Tools for Rational Drug Design

Reggio, Patricia H.

Année:

2009

Langue:

english

Fichier:

PDF, 915 KB

english, 2009

33

The Cannabinoid Receptors Volume 1 || New Insights into the Endocannabinoid System by Using Cannabinoid Receptor Knockout Mice

Reggio, Patricia H.

Année:

2009

Langue:

english

Fichier:

PDF, 497 KB

english, 2009

34

The Cannabinoid Receptors Volume 1 || Endocannabinoids as Modulators of Synaptic Signaling

Reggio, Patricia H.

Année:

2009

Langue:

english

Fichier:

PDF, 411 KB

english, 2009

35

The Cannabinoid Receptors Volume 389 || Therapeutic Applications for Agents that Act at CB1 and CB2 Receptors

Reggio, Patricia H.

Année:

2009

Langue:

english

Fichier:

PDF, 504 KB

english, 2009

36

A critical role for a tyrosine residue in the cannabinoid receptors for ligand recognition

Sean D. McAllister, Qing Tao, Judy Barnett-Norris, Kurt Buehner, Dow P. Hurst, Frank Guarnieri, Patricia H. Reggio, Katharine W. Nowell Harmon, Guy A. Cabral, Mary E. Abood

Journal:

Biochemical Pharmacology

Année:

2002

Langue:

english

Fichier:

PDF, 621 KB

english, 2002

37

Palmitoylation and membrane cholesterol stabilize μ-opioid receptor homodimerization and G protein coupling

Hui Zheng, Elizabeth A Pearsall, Dow P Hurst, Yuhan Zhang, Ji Chu, Yali Zhou, Patricia H Reggio, Horace H Loh, Ping-Yee Law

Journal:

BMC Cell Biology

Année:

2012

Langue:

english

Fichier:

PDF, 3.03 MB

english, 2012

38

Adamantyl Cannabinoids: A Novel Class of Cannabinergic Ligands

Lu, Dai, Meng, Zhaoxing, Thakur, Ganesh A., Fan, Pusheng, Steed, John, Tartal, Cindy L., Hurst, Dow P., Reggio, Patricia H., Deschamps, Jeffrey R., Parrish, Damon A.

Journal:

Journal of Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 490 KB

english, 2005

39

Mild Generation of o-Quinone Methides. Synthesis of (-)-Hexahydrocannabinol and Dihydrocannabidiol

Wang, Tiansheng, Burges, Jason P., Reggio, Patricia H., Seltzman, Herbert H.

Journal:

Synthetic Communications

Année:

2000

Langue:

english

Fichier:

PDF, 232 KB

english, 2000

40

The Bioactive Conformation of Aminoalkylindoles at the Cannabinoid CB1 and CB2 Receptors: Insights Gained from (E)- and (Z)-Naphthylidene Indenes

Reggio, Patricia H., Basu-Dutt, Sharmista, Barnett-Norris, Judy, Castro, Marie T., Hurst, Dow P., Seltzman, Herbert H., Roche, Michael J., Gilliam, Anne F., Thomas, Brian F., Stevenson, L. A.

Journal:

Journal of Medicinal Chemistry

Année:

1998

Langue:

english

Fichier:

PDF, 209 KB

english, 1998

41

The Cannabinoid Receptors Volume 17 || Structure–Activity Relationships of Classical Cannabinoids

Reggio, Patricia H.

Année:

2009

Langue:

english

Fichier:

PDF, 516 KB

english, 2009

42

Lipids, lipid rafts and caveolae: Their importance for GPCR signaling and their centrality to the endocannabinoid system

Judy Barnett-Norris, Diane Lynch, Patricia H. Reggio

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 347 KB

english, 2005

43

Inhibition of striatal dopamine release by CB1 receptor activation requires nonsynaptic communication involving GABA, H2O2, and KATP channels

Zsuzsanna Sidló, Patricia H. Reggio, Margaret E. Rice

Journal:

Neurochemistry International

Année:

2008

Langue:

english

Fichier:

PDF, 460 KB

english, 2008

44

A review of recent advances in cannabinoid research and the 1994 international symposium on cannabis and the cannabinoids

Richard E. Musty, Patricia Reggio, Paul Consroe

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 696 KB

english, 1995

45

The international cannabis research society and 1994 international symposium on cannabis and the cannabinoids

Richard E. Musty, Patricia Reggio, Paul Consroe

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 167 KB

english, 1995

46

A molecular reactivity template for cannabinoid activity

Patricia H. Reggio, Aleksander P. Mazurek

Journal:

Journal of Molecular Structure: THEOCHEM

Année:

1987

Langue:

english

Fichier:

PDF, 776 KB

english, 1987

47

Conformational Analysis and Molecular Dynamics Study: 2-Arachidonoyl-sn-glycero-3-phosphoinositol (2-AGPI) in a DOPC Bilayer

Kotsikorou, Evangelia, Lynch, Diane, Reggio, Patricia

Journal:

Biophysical Journal

Année:

2009

Langue:

english

Fichier:

PDF, 43 KB

english, 2009

48

Endogenous lipid activated G protein-coupled receptors: Emerging structural features from crystallography and molecular dynamics simulations

Hurst, Dow P., Schmeisser, Marianne, Reggio, Patricia H.

Journal:

Chemistry and Physics of Lipids

Année:

2013

Langue:

english

Fichier:

PDF, 2.12 MB

english, 2013

49

Molecular Dynamics Simulations of the Endocannabinoid N -Arachidonoylethanolamine (Anandamide) in a Phospholipid Bilayer: Probing Structure and Dynamics

Lynch, Diane L., Reggio, Patricia H.

Journal:

Journal of Medicinal Chemistry

Année:

2005

Langue:

english

Fichier:

PDF, 458 KB

english, 2005

50

Opioid receptors: toward separation of analgesic from undesirable effects

Law, Ping-Yee, Reggio, Patricia H., Loh, Horace H.

Journal:

Trends in Biochemical Sciences

Année:

2013

Langue:

english

Fichier:

PDF, 1019 KB

english, 2013